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GRK 2624
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Research
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Projects
R3: Gen-InterAna
measured (and imputed) SNPs from a certain gene, a pathway, or the whole genome (Lewis and Vassos, 2017). Considering such genetic risk scores instead of individual SNPs, which are often highly correlated [...] improved detection of associations of genes or pathways, respectively, with this outcome (Hüls et al., 2017). It is well known that not individual SNPs, but interactions of several SNPs are important for the [...] with, e.g., the elastic net, which is often employed to construct genetic risk scores (Hüls et al., 2017), were performed on both simulated and real data, e.g., from the SALIA study. The results of these …